Bayer Leverkusen v PSV Prediction and Preview | Champions League

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DavidParsons

David Parsons is an experienced sports writer with over 15 years’ expertise, creating trusted, data-driven match previews and betting content for leading sports platforms.

Published Date: September 30, 2025 9:46 PM

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Bayer Leverkusen v PSV Match Preview

Bayer Leverkusen v PSV Betting Tips and Preview – Champions League

01 October, 20:00 – Champions League
Venue: BayArena, Leverkusen

Bayer Leverkusen v PSV Match Preview

Bayer Leverkusen head into this midweek clash with confidence after extending their unbeaten run in all competitions to six matches, thanks to a hard-fought 2-1 Bundesliga victory away at St Pauli. Kasper Hjulmand’s side have looked sharp both domestically and in Europe, and they will be eager to build momentum on home soil following their opening 2-2 Champions League draw at Copenhagen.

With three wins in their last six outings, including triumphs over Eintracht Frankfurt and St Pauli, Leverkusen will feel well placed to take all three points against a PSV side already under pressure in Group B.

PSV Eindhoven, meanwhile, picked up a 2-1 Eredivisie win away at Excelsior at the weekend, but their continental campaign began in disappointing fashion. A 3-1 home defeat to Union St Gilloise on matchday one left the Dutch side with plenty of work to do, and Peter Bosz’s team now face a daunting test at the BayArena.

With Leverkusen unbeaten and PSV already playing catch-up in the group, this fixture could prove decisive in shaping both sides’ European hopes.

Bayer Leverkusen v PSV

1 Oct 20:00 - Leverkusen vs PSV - Champions League

1 Oct 20:00
Leverkusen vs PSV - Champions League

Leverkusen Win

Match Result

86/100

Reason for Tip

Bayer Leverkusen v PSV Betting Tips and Preview – Champions League

01 October, 20:00 – Champions League
Venue: BayArena, Leverkusen

Bayer Leverkusen v PSV Match Preview

Bayer Leverkusen head into this midweek clash with confidence after extending their unbeaten run in all competitions to six matches, thanks to a hard-fought 2-1 Bundesliga victory away at St Pauli. Kasper Hjulmand’s side have looked sharp both domestically and in Europe, and they will be eager to build momentum on home soil following their opening 2-2 Champions League draw at Copenhagen.

With three wins in their last six outings, including triumphs over Eintracht Frankfurt and St Pauli, Leverkusen will feel well placed to take all three points against a PSV side already under pressure in Group B.

PSV Eindhoven, meanwhile, picked up a 2-1 Eredivisie win away at Excelsior at the weekend, but their continental campaign began in disappointing fashion. A 3-1 home defeat to Union St Gilloise on matchday one left the Dutch side with plenty of work to do, and Peter Bosz’s team now face a daunting test at the BayArena.

With Leverkusen unbeaten and PSV already playing catch-up in the group, this fixture could prove decisive in shaping both sides’ European hopes.

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Current Form Guide

Bayer Leverkusen Form

Unbeaten in last 6 matches (all competitions)
Won 2-1 away at St Pauli at the weekend
Opened Champions League campaign with 2-2 draw at Copenhagen

PSV Eindhoven Form

Won 2-1 at Excelsior in Eredivisie
Lost 3-1 at home to Union St Gilloise in Champions League opener
Mixed results with several key injuries piling up

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Team News and Predicted Line-Ups

Bayer Leverkusen

Out: Robert Andrich (groin), Exequiel Palacios (groin/ineligible), Martin Terrier (Achilles), Nathan Tella (knee)
Doubt: Patrik Schick (hamstring)
Malik Tillman set to face former club PSV
Grimaldo expected to feature after scoring in Copenhagen

Predicted XI (3-4-2-1):
Flekken; Quansah, Bade, Tapsoba; Tape-Kobrissa, Garcia, Fernandez, Grimaldo; Tillman, Ben Seghir; Kofane

PSV Eindhoven

Out: Van Bommel (knee), Plea (knee), Boadu (hamstring), Sildillia (thigh)
Doubt: Sergino Dest, Ricardo Pepi, Anass Salah-Eddine
Ivan Perisic and Joey Veerman expected to start, Veerman with 6 goal contributions this season
Matej Kovar (on loan from Leverkusen) likely to start in goal

Predicted XI (4-3-3):
Kovar; Junior, Flamingo, Gasiorowski, Obispo; Schouten, Saibari, Veerman; Wanner, Til, Perisic

Bayer Leverkusen v PSV Prediction

Leverkusen are in excellent form and look strong at both ends of the pitch, while PSV are still reeling from their poor start in Europe and struggling with multiple absentees. With home advantage and greater depth, the German side should come out on top.

Prediction: Bayer Leverkusen win

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Bayer Leverkusen v PSV Betting Tips

The Bundesliga side have the momentum and quality to take control of PSV with three points here.

Bayer Leverkusen win @ 1.85 (Paddy Power)

Bayer Leverkusen v PSV

1 Oct 20:00 - Leverkusen vs PSV - Champions League

1 Oct 20:00
Leverkusen vs PSV - Champions League

Leverkusen Win

Match Result

86/100

Reason for Tip

Bayer Leverkusen v PSV Betting Tips and Preview – Champions League

01 October, 20:00 – Champions League
Venue: BayArena, Leverkusen

Bayer Leverkusen v PSV Match Preview

Bayer Leverkusen head into this midweek clash with confidence after extending their unbeaten run in all competitions to six matches, thanks to a hard-fought 2-1 Bundesliga victory away at St Pauli. Kasper Hjulmand’s side have looked sharp both domestically and in Europe, and they will be eager to build momentum on home soil following their opening 2-2 Champions League draw at Copenhagen.

With three wins in their last six outings, including triumphs over Eintracht Frankfurt and St Pauli, Leverkusen will feel well placed to take all three points against a PSV side already under pressure in Group B.

PSV Eindhoven, meanwhile, picked up a 2-1 Eredivisie win away at Excelsior at the weekend, but their continental campaign began in disappointing fashion. A 3-1 home defeat to Union St Gilloise on matchday one left the Dutch side with plenty of work to do, and Peter Bosz’s team now face a daunting test at the BayArena.

With Leverkusen unbeaten and PSV already playing catch-up in the group, this fixture could prove decisive in shaping both sides’ European hopes.

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Conclusion

Bayer Leverkusen are unbeaten and building confidence under Kasper Hjulmand, while PSV’s opening defeat leaves them under pressure. With the BayArena crowd behind them, Leverkusen should have too much for the Dutch side.

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