NFL Moneyline Acca Week 5 Tips & Picks

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Tyler Smith

An enthusiastic sports writer with a passion for Football, American Sports and Formula 1, bringing sharp insight and informed betting analysis to every weekend.

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NFL Week 5 Preview and Analysis

We’re officially a quarter of the way through the 2025 NFL season, and Week 5 promises to bring more clarity as teams separate the contenders from the pretenders. Matchups this weekend feel especially loaded: some squads with strong early statements will try to cement momentum, while others still scrambling for answers may show signs of pressure mounting. After four weeks of surprises, injuries, and breakout performances, this week could be the one that begins to define the playoff picture—and reveals who’s merely riding hot streaks.

Buffalo remains the lone unbeaten squad in the AFC, standing at 4-0 and looking to sharpen their edge as division matchups loom. Meanwhile, teams like Baltimore are fighting to get back on track. The Ravens’ 1-3 start has raised eyebrows, especially with Lamar Jackson’s hamstring injury and several key defensive personnel sidelined. On the flip side, Houston finally broke through with their first win, aided by a strong defensive showing and emerging playmakers like rookie Woody Marks.

For bettors, analysts, and fantasy managers alike, the trends developing now are rich with value. Young quarterbacks such as C.J. Stroud and Anthony Richardson continue to show flashes of franchise potential, while offenses in some teams are gaining efficiency versus defenses that still look shakier than expected.  Matchups like Chiefs vs Saints and others highlighted by sharp-money action suggest some games may hinge on momentum and injury reports. As Week 5 unfolds, we’ll be keeping close tabs on which teams respond under pressure—and, just as importantly, which ones begin to falter.

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NFL Week 5 Matchups

After an exciting opening weekend full of standout performances, Week 5 kicks off with anticipation as teams seek continuity, responses, or quick rebounds.

🏈 Week 5 Matchups

Thursday, October 2

  • San Francisco 49ers at Los Angeles Rams

Sunday, October 5

  • Minnesota Vikings at Cleveland Browns (London)

  • Houston Texans at Baltimore Ravens

  • Miami Dolphins at Carolina Panthers

  • Las Vegas Raiders at Indianapolis Colts

  • New York Giants at New Orleans Saints

  • Dallas Cowboys at New York Jets

  • Denver Broncos at Philadelphia Eagles

  • Tennessee Titans at Arizona Cardinals

  • Tampa Bay Buccaneers at Seattle Seahawks

  • Detroit Lions at Cincinnati Bengals

  • Washington Commanders at Los Angeles Chargers

Sunday Night / Primetime

  • New England Patriots at Buffalo Bills

Monday Night Football

  • Kansas City Chiefs at Jacksonville Jaguars (Monday, October 6)

🏈 Key Matchups

🔥 San Francisco 49ers at Los Angeles Rams (Thursday Night)

A heavyweight NFC West clash right out of the gate. The 49ers are once again among the NFC’s elite, while the Rams look to prove they can keep pace in the division. Divisional games in primetime often swing playoff positioning, and this one has all the makings of a statement game.


🌍 Minnesota Vikings vs. Cleveland Browns (London Game)

The first of the international showcases in London. The Vikings’ evolving offense takes on a Cleveland team built around defense and a bruising run game. London games often bring unpredictable results, and this one puts two physical, playoff-hungry squads on display for a global audience.


🛡 Dallas Cowboys at New York Jets

A battle of two fierce defenses with major star power. The Cowboys’ pass rush will test the Jets’ offensive line, while New York’s secondary looks to contain Dallas’ playmakers. This has low-scoring slugfest written all over it, and could carry big AFC/NFC playoff implications.


🐴 Denver Broncos at Philadelphia Eagles

The Eagles are aiming to stay atop the NFC East, while the Broncos—under new leadership—are fighting to prove they can compete in the AFC. Philadelphia’s elite roster depth makes them favorites, but Denver’s defense could cause problems if Jalen Hurts isn’t sharp.


🏹 Detroit Lions at Cincinnati Bengals

Two explosive offenses with playoff aspirations square off. Jared Goff and the Lions’ attack go toe-to-toe with Joe Burrow and the Bengals in what could easily be the game of the week. Expect fireworks, as both teams rely on high-powered passing games and strong playmakers.


🏆 New England Patriots at Buffalo Bills (Sunday Night Football)

A classic AFC East rivalry under the primetime lights. Buffalo remains the standard in the division, but New England’s rebuilt roster is eager to challenge. If the Patriots can slow Josh Allen and make this a grind-it-out affair, it could be closer than expected.


Kansas City Chiefs at Jacksonville Jaguars (Monday Night Football)

A potential AFC playoff preview. Patrick Mahomes leads the reigning powerhouse Chiefs into Jacksonville against Trevor Lawrence and the Jaguars, who continue to grow into legitimate contenders. This primetime battle could have long-term seeding implications.

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Why Each Leg Makes Sense

New York Giants Moneyline

Jaxson Dart has the reigns now in New York and got off to a perfect start with a win against the LA Chargers who were previously unbeaten. This was somewhat of a shock as we had the chargers in our Week 4 moneyline acca. Dart really surprised me and showed some fantastic poise in his first ever competitive start. Even with Malik Nabers going down with an ACL injury, the Giants still kept moving forward and their defence limited the chargers to little. They come up against a Saints side who while they showed glimpses against the Bills, they didnt really force the Bills to get out of second gear. I expect this to be a close match, but I fancy the Giants to get the better of it.

Indianapolis Colts Moneyline

The Colts sit at 3-1 and if you ask any Colts fan at the start of the season, they would take that in a heartbeat. Having Danny Jones at QB is rather unpredictable but he has become a lot more settled and Jonathan Taylor has stayed fit and produced really positive performances in the run game. They face the raiders who are 1-3 suffering a close loss at the hands of the Bears. The Raiders are a work in progress with RB Jeanty stealing the show with 3 TD’s in his last game and Geno Smith managing the QB position better than previous seasons. Truth be told, the Raiders dont have enough assets to be competitive and the Colts should be able to establish their blueprint to win the game.

LA Chargers Moneyline

The Chargers come in off the back of their first loss of the season and one they would love to have back. They lost star OL Joe Alt and this seemingly affected the flow of the team and QB Herbert. They were still good and efficient but didn’t have enough to get over the line. This week they face a Commanders side who have been disappointing so far. Jayden Daniels has suffered injuries and struggled, the defence has been less impactful and the positive feelings from last season have slowed. However, this will be a tight occasion and provides us some good value on the betting market.

Arizona Cardinals Moneyline

A relatively straight forward selection here, as straight forward as anything can be in betting. The Cardinals are simply better than the Titans in every area. The Titans have hope in Cam Ward who could be a good player in the future, but if they dont surround him with a positive system, better players and a defence that can actually limit the amount of points given up, they  will have no hope. They got shutout this weekend, not scoring a single point. The Cardinals selection, while not exciting, provides us a small boost to the overall odds.

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Where to Watch the NFL in the UK and the World

Watching the NFL in the UK

Sky Sports (Pay-TV and Streaming)

  • Sky Sports NFL has returned as the dedicated NFL channel for UK and Ireland audiences, launching September 1, 2025, under a new multi-year rights agreement running through 2027–28.

  • The deal brings a nearly 50% increase in live NFL coverage, including:

    • A second Sunday game at 6 p.m. local time

    • Up to two additional Sunday evening games at 9 p.m.

    • All London and European games

    • Thursday Night, Sunday Night, and Monday Night Football

    • NFL RedZone, Thanksgiving games, playoffs, Pro Bowl, and Super Bowl LX coverage

  • You can access Sky Sports NFL via:

    • Sky satellite (channel 412)

    • Sky Stream (channel 410)

    • NOW (Sky’s no-contract streaming platform)

    • Virgin Media, among other third-party providers

Channel 5 / 5ACTION (Free-to-Air)

  • A new free-to-air broadcast deal lets UK viewers watch two live NFL games each Sunday:

    • One at 6 p.m. on Channel 5

    • Another at 9 p.m. on 5ACTION, which will be branded “5NFL” during NFL evenings

  • Coverage includes:

    • Super Bowl, London & Dublin Games, Thanksgiving, and selection playoff games

    • A family-friendly, interactive studio show called NFL: Big Game Night, hosted by Dermot O’Leary, Sam Quek, and Osi Umenyiora

DAZN – NFL Game Pass International

  • Through DAZN in the UK, you can subscribe to NFL Game Pass International, offering:

    • Live and on-demand access to every regular-season and playoff game, plus the Super Bowl

    • Full access to NFL RedZone, NFL Network shows, replays, and exclusive content like press conferences and analysis

  • Pricing in the UK is available via DAZN (typically around £169.99 annually or installments discounted)

  • Note: DAZN in the UK will broadcast two Sunday games per week on a 24-hour delay as part of simulcast rules


Watching the NFL Around the World (Outside the UK)

DAZN – NFL Game Pass International

  • Globally (excluding the USA & China), NFL Game Pass International remains the primary way to watch:

    • All regular-season and playoff games live and on-demand (~335 games per season)

    • NFL RedZone, NFL Network, plus archival content like documentaries and NFL originals

  • Available in countries such as Spain, Germany, Italy, France, and beyond with localized pricing

Region-Specific Broadcasters

  • Across Europe and other regions, several broadcasters hold local NFL rights:

    • Spain: DAZN

    • Germany/Austria/Switzerland: DAZN; RTL Deutschland also covers select games free-to-air

    • France: M6 Group and beIN Sports

    • Italy/Netherlands: DAZN and ESPN

    • Nordic countries: TV 2 Sport (Denmark), TV4 (Sweden/Finland)

    • More in: Portugal, Poland, Greece, Hungary, etc

NFL Sunday Ticket

  • Available in Canada on DAZN

  • Optionally in Mexico, Central America, South America & the Caribbean through platforms like Sky México, Vrio, and Vivo TV

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